Majors and minors are offered in the departments of English and Ethnic Studies. English also offers three graduate degrees: the master of arts degree in English and American literature, the master of fine arts degree in creative writing, and the master of fine arts degree in book art and creative writing. Majors and minors are also offered in French and Francophone studies, Latin American studies, literary and cultural studies, and Spanish and Spanish American studies.

The division offers minors only in book art and journalism.

In addition, Letters offers required and elective courses for programs and departments outside the division including American Studies; Intermedia Arts; Political, Legal, and Economic Analysis (PLEA); and Public Policy.